Fig. 5: Somatosensory input alters rsFC in regions responsive to phasic stimulation.

a Somatosensory input is delivered using pulsed air flows delivered to each side of the face. b Signal changes over time in S1, in response to phasic airflow stimulation delivered in blocks (pink rectangles) to the left (top) and right (bottom) sides of the face. Shading around time courses denotes SEM over n = 6–7 animals. c Mean responses to block stimulation on the left and right sides over n = 6–7 animals. d Maps of the mean response to left and right block stimulation in (b). Results for voxels with significant responses over animals were shown (two-sided t test p ≤ 0.05, n = 7). Bregma coordinates in mm are indicated in yellow. e Seed-based maps of rsFC acquired in the absence (top) and presence (bottom) of tonic bilateral air flow stimulation. Seed locations in S1 (arrowheads) correspond to functional responses in (d). Regression coefficients indicated for voxels with t test p ≤ 0.01 over n = 7 animals. f Mean homotopic S1BF regression coefficients in the absence (dark blue) vs. presence (magenta) of tonic airflow stimulation over n = 7 animals, showing a significant difference with paired t test p = 0.04.