Fig. 8: Structural basis of GH168 family substrate specificity.
From: Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota
a Structural comparison analysis of Rho5174 with X-ray crystal structures of PbFucA, Fun168A, and the Alphafold models of GH168 enzymes from strains 892 and 913, and Fun168D from W. funcanilytica CZ1127T. Conserved and variable residues are colored in red and blue, respectively. b Structure weighted sequence alignment of GH168 enzymes from 892 and 913 strains, PbFucA from P. bacterium K23_9 and Fun168A and Fun168D from W. funcanilytica CZ1127T. Catalytic residues are highlighted with green circles. Residues interacting with fucose moieties in the X-ray crystal structure of FunA168A-Fuc4 are highlighted with red triangles.
