Fig. 3: Associations between BMFF and bone mineral density at each site.
From: Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank
Linear regression for rank-normalized BMFF vs BMD (g/cm2) at each skeletal site, as follows: A Spine BMFF vs spine BMD (n = 40,485); B Femoral head BMFF vs femoral neck (left) BMD (n = 37,967); C Total hip BMFF vs femoral trochanter (left) BMD (n = 38,007); D Femoral diaphysis BMFF vs femoral shaft (left) BMD (n = 37,015). The smaller sample sizes for the linear regressions between BMFF and BMD at the respective skeletal sites compared to the analyses in Fig. 2 are the result of not all participants (for whom BMFF was measured) having complete BMD measurements from DXA-scans. Linear regression summary statistics (Beta coefficients [β], R-squared [R2] and p-values [p]) for the multivariate linear regression models, adjusted for Sex, Age and BMI, are shown in the top-right corner of each plot.
