Fig. 6: MAGMA Gene-set analysis for Meta-GWAS in the white unrelated population.
From: Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank
Bubble plot for gene sets significantly enriched among the BMFF-associated genes identified by meta-GWAS in the white participants (males and females combined). In MAGMA gene-set analysis (two-sided), each gene set (or GO term) was tested for enrichment. Significance is based on Bonferroni-corrected p values, as indicated by the color of each bubble. The size of each bubble represents the number of genes in each gene set. To streamline the presentation, the names of two gene sets (indicated by *) have been abridged to fit within the figure; these gene set’s full names are ‘WP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA’ and ‘WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_PREGNANCY_AND_LACTATION_STAGE_3_OF_4’.
