Fig. 6: PheWAS results for RA case-control and progression risk scores in UK Biobank. | Nature Communications

Fig. 6: PheWAS results for RA case-control and progression risk scores in UK Biobank.

From: Integrating electronic health records and GWAS summary statistics to predict the progression of autoimmune diseases from preclinical stages

Fig. 6

A PheWAS results from CC-PRS of RA. B PheWAS results from GPS-PRS of RA. The y-axis represents the −log10(p-value) for each PheWAS code, derived using a two-sided Chi-square test after fitting a multivariate logistic regression model. The x-axis displays different PheWAS code categories. Each point corresponds to a specific PheWAS code, with downward and upward pointing triangles indicating negative and positive associations between disease status defined by the PheWAS code and the PRS, respectively.

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