Table 2 Generalizability test of CLEAN selection methods when calibrating on 380 data points from New and testing on all 149 samples from Price (56 EC classes)

From: Functional protein mining with conformal guarantees

Method

Precision

Recall

F1

AUC

Conformal (α = 1.5)

55.98

49.34

49.62

74.59

Max-sep

58.44

46.71

49.47

73.34

P-Value

59.26

47.74

47.77

72.34

  1. Nearly all of New is used for calibration, as increasing the size of the calibration set progressively tightens the loss coverage, detailed in Eq. (5). Bold values indicate the best-performing method for each metric (higher is better).