Fig. 5: Landing probabilities of ex vivo IFT trains on detyrosinated/tyrosinated microtubules. | Nature Communications

Fig. 5: Landing probabilities of ex vivo IFT trains on detyrosinated/tyrosinated microtubules.

From: Tubulin tyrosination/detyrosination regulate the affinity and sorting of intraflagellar transport trains on axonemal microtubule doublets

Fig. 5

A, B Box plots of landing probability of anterograde or retrograde IFT trains on untreated (green plots), carboxypeptidase-A treated (orange plots), or tubulin tyrosine ligase treated (yellow plots) microtubules. Each data point indicates individual demembranation events in each case, across 3 biological replicates in each case. Statistics by one-way ANOVA. p-values as shown. Box bounds represent 25% and 75% quartiles. Line represents median. Box whiskers represent maxima and minima. C, D Relative change in anterograde (green plot) or retrograde (magenta plot) IFT train landing probabilities (normalized within samples from (A) and (B) w.r.t. relative microtubule tyrosination (see Fig. S9). n and N as in (A) and (B) for each case. Erros bars represent Mean ± S.E. on both axes.

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