Fig. 4: The influence of PNP on the gut bacterial metabolites using metabolomics analysis.
From: Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites
A–D GF mice and hFB mice treated with PNP (0.5 g/kg, body weight) every other day for two months. Gut feces from GF and hFB mice suspended in PBS (1.0 g/ml). After centrifuging at 10,000 × g, the supernatant was used for metabolomics analysis using 2D-LC-MS/MS. Heatmap indicating top 10 bacterial metabolites up- or down-regulated by ELN (E) and Nano10 (N10) in hFB mice normalized to GF. Source data are provided as a Source Data file.
