Fig. 2: Cross-flow microfluidic catalysis.
a Chemical structure of the reactants, * = reactive –CH2 group; DtBut and DEt are the diffusivities of t-But-CA and Et-CA, respectively; b illustration of cross-flow microfluidic reaction using MOF thin film as catalyst, P circulating pump, R reactant and product chamber, yellow dotted line indicates the flow path, right MOF catalyst thin film with controllable thickness, LD diffusion length; c TOF after 24 h at 70 °C for one pot reaction with smaller MOF submicron-sized particles and in cross-flow microfluidic reaction using UiOTF1 (5 mL/min flow-rate), 1 mmol of benzaldehyde and nucleophiles each in 10 mL of ethanol. Conversion % is calculated using 1H NMR.
