Fig. 3: Genomic context around the deletion (indicated by the red box) at the GSDMD locus. | Nature Communications

Fig. 3: Genomic context around the deletion (indicated by the red box) at the GSDMD locus.

From: Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility

Fig. 3

The genomic context includes the Hi-C interaction sourced from Rao et al.114, annotations for promoters and enhancers from the GeneHancer database, H3K4me1, and H3K27ac ChIP-seq tracks for primary B cells, primary T cells and osteoblasts from the Roadmap Epigenomics dataset, H3K4me1, H3K27ac or CTCF ChIP-seq tracks for HUVEC, HMEC, NHEK, HeLa-S3, a layered H3K27ac track on 7 cell lines (GM12878, H1-hESC, HSMM, HUVEC, K562, NHEK and NHLF), and transcription factor (TF) binding sites tracks for Liver, K562, HepG2 and GM12878 from ENCODE data set. All the annotations were visualized in the UCSC Genome Browser.

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