Fig. 1: Manhattan plot summarising genome-wide associations with psoriasis susceptibility.
x-axis, genomic position; y-axis, −log10(P-value) of association (two-sided Z-test, unadjusted for multiple tests); red and green points, regions previously and newly associated, respectively, with psoriasis susceptibility at genome-wide significance (P = 5 × 10−8) in European ancestry populations; solid horizontal line, genome-wide significance threshold; dotted horizontal line, y-axis break at 10−30; chromosomes (labelled 1–22) are alternately shaded for clarity.
