Fig. 4: Background effects on SR parameters.
From: Parameterized resetting model captures dose-dependent entrainment of the mouse circadian clock
a Prediction model of the background effect. Dashed arrows represent SR amplitude for background stimuli (BK). Solid arrows represent the SR amplitude induced by the additional stimulus. b Attenuation of SR amplitude depends on background concentration. c The decay of background concentration during the culture. Solid and dashed lines indicate the concentration of a stimulating chemical or molecules in the medium without and with decay, respectively. d SR amplitude for forskolin and dexamethasone with background effects as a function of fold change. e, f Model predictions of background effect without (e) and with (f) background decay. SR singularity response, BK background stimuli.
