Table 1 siRNA candidates grouped by priority
Priority | Gene symbol | Entrez gene name | Type |
|---|---|---|---|
Priority 1 | ABCA6 | ATP binding cassette subfamily A member 6 | Transporter |
ABHD17B | Abhydrolase domain containing 17B | Peptidase | |
ALG10 | ALG10, alpha-1,2-glucosyltransferase | Enzyme | |
CHD8 | Chromodomain helicase DNA binding protein 8 | Enzyme | |
CTRC | Chymotrypsin C | Peptidase | |
LMLN | Leishmanolysin like peptidase | Peptidase | |
PSMC4 | Proteasome 26S subunit, ATPase 4 | peptidase | |
SLC25A32 | Solute carrier family 25 member 32 | Transporter | |
SUPT6H | SPT6 homolog, histone chaperone | Transcription regulator | |
TGFBR2 | Transforming growth factor beta receptor 2 | Kinase | |
YY1 | YY1 transcription factor | Transcription regulator | |
Priority 2 | BRD4 | Bromodomain containing 4 | Kinase |
EIF1B | Eukaryotic translation initiation factor 1B | Translation regulator | |
GPX7 | Glutathione peroxidase 7 | Enzyme | |
KLF6 | Kruppel like factor 6 | Transcription regulator | |
Priority 3 | AQP3 | Aquaporin 3 (Gill blood group) | Transporter |
CLPP | Caseinolytic mitochondrial matrix peptidase proteolytic subunit | Peptidase | |
FGF2 | Fibroblast growth factor 2 | Growth factor | |
HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Enzyme | |
MAPKAPK2 | Mitogen-activated protein kinase-activated protein kinase 2 | Kinase | |
MFHAS1 | Malignant fibrous histiocytoma amplified sequence 1 | Other | |
NEK4 | NIMA related kinase 4 | Kinase | |
SLC25A29 | Solute carrier family 25 member 29 | Transporter |