Fig. 3: In vitro intestinal mucus penetration performance. | Nature Communications

Fig. 3: In vitro intestinal mucus penetration performance.

From: Bioactive nanomotor enabling efficient intestinal barrier penetration for colorectal cancer therapy

Fig. 3: In vitro intestinal mucus penetration performance.

a Schematic diagram of the microfluidic channel. b CLSM images of the motility of nanomotors in a two-outlet microfluid channel. c The corresponding movement distance (n = 3 independent experiments). d Schematic diagram of transwell assay composed of mucus and gels. e The ratio of nanoparticles penetrated into basal chamber after 5 min of incubation in apical chamber (n = 3 independent experiments). f Schematic diagram of nanomotor penetration intestinal mucus barrier. g CLSM fluorescent images nanoparticle penetration intestinal mucus barrier for 5 min. h MFI of red fluorescence in the dotted box in (g) (n = 3 independent experiments). Data are presented in the form of mean values ± SD. Significance was assessed via one-way ANOVA with Tukey’s post hoc test. Source data are provided as a Source Data file.

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