Fig. 4: scRNAseq in BAL cells reveals lymphocytic enrichment.

a tSNE visualization of re-clustered lymphocytes (all conditions together). b Bubble plot and c. violin plot depicting expression of canonical marker genes used for identification of lymphocyte populations. d–m Comparison of nine identified lymphocyte clusters between the BCG (
) or ΔsigH (
) -vaccinated groups showing cluster 0 (d), cluster 1 (e), cluster 2 (f), cluster 3 (g), cluster 4 (h), cluster 5 (i), cluster 6 (j), cluster 7 (k), cluster 8 (l), and cluster 9 (m). Data is presented as mean ± SEM and P-values are derived from Mann-Whitney U test.