Fig. 1: Single cell transcriptomic/AbSeq profiling of CD34+cells from human BM. | Nature Communications

Fig. 1: Single cell transcriptomic/AbSeq profiling of CD34+cells from human BM.

From: Continuous map of early hematopoietic stem cell differentiation across human lifetime

Fig. 1: Single cell transcriptomic/AbSeq profiling of CD34+cells from human BM.The alternative text for this image may have been generated using AI.

a UMAP visualization of gene expression-based clustering analysis of 62,277 CD34+ cells from 15 donors with cluster annotation. b Feature plots for the expression of human stem cell gene markers. c Violin plots showing the surface protein expression of CD90, CD38 and CD45RA, detected by Transcriptomic/AbSeq. d Dot-plot visualization of gene expression of previously defined cell type-specific markers. e Distribution of FACS-sorted CD34+CD38− cells in respective clusters and visualized on the UMAP, demonstrating enrichment in most immature cell clusters.

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