Fig. 7: Amino acid changes and variant analyses in the D701N cluster. | Nature Communications

Fig. 7: Amino acid changes and variant analyses in the D701N cluster.

From: Cross-species and mammal-to-mammal transmission of clade 2.3.4.4b highly pathogenic avian influenza A/H5N1 with PB2 adaptations

Fig. 7

a Amino acid substitutions are listed for the 13 H5N1 viruses in the D701N cluster (Fig. 2), including 11 sequenced for this study and 2 from Peru. These mutations were not observed in wild birds or poultry sequenced in this study, except for the sanderling that is part of the D701N cluster. b Frequency of single nucleotide variants (SNV), and amino acid substitutions for A/H5N1 genomic positions were calculated for the 701N cluster genome segments employing the raw data obtained by Illumina sequencing (when available) or nanopore sequencing. SNV analyses were also performed for all avian segments (Supplementary Fig. 4 and Supplementary Data). Positions are numbered according to the reference genomes OQ352545-OQ352552. Viral isolates are indicated on the left and the are colored according to their geographical origin: Northern Chile (blue), North-Central Chile (brown) or Central Chile (green).

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