Fig. 1: Study overview detailing cohorts used for analyses within ERpHER2n and ERpHER2p disease.

. A Analyses comparing ERpHER2n-HER2E to the PAM50 subtypes LumA and LumB within ERpHER2n disease. B Analyses comparing ERpHER2n-HER2E to ERpHER2p disease subtyped as PAM50 HER2E or another subtype. ACT adjuvant chemotherapy, TME tumor microenvironment, DEG Differentially expressed gene, CNA Copy number alteration.