Fig. 1: HPV vaccine-type antibody subclass responses in Fijian girls. | Nature Communications

Fig. 1: HPV vaccine-type antibody subclass responses in Fijian girls.

From: Systems serology analysis shows IgG1 and IgG3 memory responses six years after one dose of quadrivalent HPV vaccine

Fig. 1

Violin plots show total IgG, IgM, IgA1, IgA2 MFI for HPV16 (A) and HPV18 (C), and IgG subclass MFI i.e. IgG1, IgG2, IgG3, IgG4 for HPV16 (B) and HPV18 (D) median fluorescence intensity (MFI) or International Units/mL (IU/mL) six years following the last dose of 4vHPV vaccine (Pre) or 28 days post-2vHPV booster (Post). The median of each group is denoted by a black horizontal line. Statistical significance was calculated using the Kruskal-Wallis test and corrected for multiple comparisons with Dunn’s test. A positive antibody response is defined as being above median BPV (negative control antigen) MFI or IU/mL (IgG). Definitions: 0D 0-dose (n = 20), 1D 1-dose (n = 20), 2D 2-dose (n = 21), 3D 3-dose (n = 19).

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