Fig. 2: HPV vaccine-type Fc-mediated antibody responses in Fijian girls. | Nature Communications

Fig. 2: HPV vaccine-type Fc-mediated antibody responses in Fijian girls.

From: Systems serology analysis shows IgG1 and IgG3 memory responses six years after one dose of quadrivalent HPV vaccine

Fig. 2: HPV vaccine-type Fc-mediated antibody responses in Fijian girls.The alternative text for this image may have been generated using AI.

Fc receptor responses (FcγR2A, FcγR2B, FcγR3A) and ADCP function against HPV16 and HPV18 (A) were measured at six years following the last dose of 4vHPV vaccine (Pre) or 28 days post-2vHPV booster (Post). The median of each group is denoted by a black horizontal line. A positive response is defined as being above the median of control antigen BPV for Fc receptors, or the median of a seronegative control serum for ADCP. Statistical significance was calculated using the Kruskal-Wallis test and corrected for multiple comparisons with Dunn’s test. Correlation between FcγR2A and ADCP for HPV16 and HPV18 (B) was assessed using Spearman’s rank test. Definitions: 0D 0-dose (n = 20), 1D 1-dose (n = 20), 2D 2-dose (n = 21), 3D 3-dose (n = 19).

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