Fig. 2: HPV vaccine-type Fc-mediated antibody responses in Fijian girls. | Nature Communications

Fig. 2: HPV vaccine-type Fc-mediated antibody responses in Fijian girls.

From: Systems serology analysis shows IgG1 and IgG3 memory responses six years after one dose of quadrivalent HPV vaccine

Fig. 2

Fc receptor responses (FcγR2A, FcγR2B, FcγR3A) and ADCP function against HPV16 and HPV18 (A) were measured at six years following the last dose of 4vHPV vaccine (Pre) or 28 days post-2vHPV booster (Post). The median of each group is denoted by a black horizontal line. A positive response is defined as being above the median of control antigen BPV for Fc receptors, or the median of a seronegative control serum for ADCP. Statistical significance was calculated using the Kruskal-Wallis test and corrected for multiple comparisons with Dunn’s test. Correlation between FcγR2A and ADCP for HPV16 and HPV18 (B) was assessed using Spearman’s rank test. Definitions: 0D 0-dose (n = 20), 1D 1-dose (n = 20), 2D 2-dose (n = 21), 3D 3-dose (n = 19).

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