Fig. 4: Principal component analysis (PCA) of vaccine-type HPV antibody features across unvaccinated and 4vHPV vaccinated Fijian girls. | Nature Communications

Fig. 4: Principal component analysis (PCA) of vaccine-type HPV antibody features across unvaccinated and 4vHPV vaccinated Fijian girls.

From: Systems serology analysis shows IgG1 and IgG3 memory responses six years after one dose of quadrivalent HPV vaccine

Fig. 4

PCA analyses and loading plots of log-transformed, LASSO-selected HPV16/18 antibody features in unvaccinated (0D, n = 20) or 4vHPV-vaccinated individuals (1D, 1-dose, n = 20; 2D, 2-dose n = 21; 3D, 3-dose, n = 19) six years following their last dose of vaccine, and one month after a 2vHPV booster dose. The mean of each group is represented by the large solid circles in the PCA plot, with coloured ellipses representing the 95% confidence level of each dosage group. Bars on the loading plot show the contribution of each LASSO-selected antibody feature to PC1 in ascending order.

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