Fig. 7: In vivo therapeutic evaluation of phototherapy mediated by EcN@INX-2.

a Schematic diagram of the flow of in vivo treatment experiments in female mice. b The changes in tumor volume in different treatment groups during the treatment cycle (n = 5 mice). c Digital photographs of tumor tissue and tumor weight (d) from each group at the end of treatment observation (n = 5 mice). e Representative H&E and immunofluorescence staining of TUNEL (red fluorescence) and Ki-67 (green fluorescence) in tumor tissues following various treatments. The cell nuclei were stained with DAPI (blue fluorescence). (Scale bar: 50 µm). Data are presented as mean ± SD (n = 5 mice). For (e), experiment was repeated three times independently with similar results. For (b and d), statistical analyzes were performed using one-way ANOVA. Source data are provided as a Source Data file.