Fig. 3: Intra-individual TCR sharing at different time points. | Nature Communications

Fig. 3: Intra-individual TCR sharing at different time points.

From: Longitudinal single cell profiling of epitope specific memory CD4+ T cell responses to recombinant zoster vaccine

Fig. 3: Intra-individual TCR sharing at different time points.

A Circos style plot demonstrating clonal sharing within individual donors, across timepoints. Clone groups were identified by the sharing of identical β- and α-chain T cell receptor CDR3 junction sequences at the nucleotide level. Outer circle and arcs connecting cells are colored by tetramer grouping. Inner circle indicates the timepoint. B Circos style plot demonstrating clonal sharing within and across donors at all timepoints. Clone groups were identified by the sharing of identical β- and α- chain T cell receptor CDR3 junction sequences at the amino acid level. Outer circle and arcs connecting cells are colored by donor/tetramer grouping. Inner circle indicates the timepoint.

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