Fig. 1: Overall structure of GlyT1 in the apo state. | Nature Communications

Fig. 1: Overall structure of GlyT1 in the apo state.

From: Modulation of the human GlyT1 by clinical drugs and cholesterol

Fig. 1: Overall structure of GlyT1 in the apo state.The alternative text for this image may have been generated using AI.

a, b, Cryo-EM density map and overall structure of the GlyT1 in the inward-facing apo state (GlyT1Apo-in). Micelle is colored grey, GlyT1 is colored light pink, and TM1 is highlighted with hot pink. N- and C- termini are labeled with spheres colored hot pink and light pink, respectively. c Surface electrostatic potential map of the GlyT1Apo-in. Unwound TM1a and TM6b form a vestibule toward the intracellular side.

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