Fig. 4: Morphology characterization using different types of amphiphilic block copolymers and theoretical calculation of interaction energy.
From: Designing polymersomes with surface-integrated nanoparticles through hierarchical phase separation
a Nanoarchitectures prepared by co-assembly of PTM (1 mg mL−1) with 1 mg mL−1 each of PEG44-P(AIE)14, PEG44-b-PS200, and PEG44-PDLLA120, respectively. Scale bar = 500 nm. b Characterization of polymersomes prepared by co-assembly of PEG44-P(AIE)8 with two PTM variants (TATQ and TPE-TATQ). Scale bar = 500 nm/Insert = 200 nm. c Morphological characterization of DiD load polymersomes by SEM (left) and dry-TEM (right). Scale bar = 1 μm (left) and 500 nm (right). d Chemical structures of PTM and its variants. In green the AIE moiety is depicted. e Interaction energy analysis of the AIE fragments of PEG44-P(AIE)8 (P(AIE)) with PTM, its variants (TPE-TATQ and TATQ), and P(AIE) in the solvent phase and gas phase via DFT calculations. f DFT calculated structures of the AIE fragment of PEG44-P(AIE)8 interacting with PTM, TPE-TATQ, TATQ, and another AIE fragment (polymer @ polymer). The AIE fragment is highlighted in blue (except in the polymer @ polymer group), while PTM and its variants are depicted in pink.
