Fig. 6: Docking results of the predicted interactions and performance comparison on different scales of labeled data.

A–F The docked poses for the predicted interactions between six potential drugs (i.e., Palbociclib, Granisetron, Axitinib, Canertinib dihydrochloride, Doramapimod, and Mubritinib, where Palbociclib is the reference drug) and the CDK 6. G The performances of DTIAM and baseline models trained on different scales of labeled data (i.e., 20%, 40%, 60%, and 80%) in DTI, DTA, and MoA prediction tasks under the warm start settings.