Fig. 1: Cohort selection.
From: Long COVID after SARS-CoV-2 during pregnancy in the United States
a Selection of females with SARS-CoV-2 infection during pregnancy or not, from the PCORnet cohort and N3C cohort. The SARS-CoV-2 infection was between March 1st, 2020, and October 31, 2022, and follow-up to June 1st, 2023. b Study design. The post-acute sequelae of SARS-CoV-2 infection (PASC), or Long COVID, outcomes were ascertained from day 30 after the SARS-CoV-2 infection and the adjusted risk was computed at 180 days after the SARS-CoV-2 infection. Two exposure groups are pregnant individuals who acquired SARS-CoV-2 during pregnancy as illustrated in b compared with outside of pregnancy. The pregnant group was compared with exactly matched non-pregnant females on site region, age, infection time, acute severity, and selected baseline comorbidities including diabetes, hypertension, autoimmune or immune suppression, mental health disorders, severe obesity, and asthma with a ratio of 1:3.
