Fig. 6: Asymmetric connectivity between different subpopulations of excitatory neurons.

A Trial averaged traces from a paired recording between connected Chrim⁺ (red) →Opsin^- (black) pyramidal neurons (top) and an enlarged view of the EPSPs (bottom). B Trial averaged traces from a paired recording between connected Opsin^-→Chrim⁺ pyramidal neurons (top) and an enlarged view of the EPSPs (bottom). C Mean ± SEM EPSP amplitudes of synaptic connections were significantly stronger in the direction of Chrim⁺→Opsin^- connections compared to Opsin^-→Chrim⁺ connections; n = 5, n = 7, p = 0.021, two-sided unpaired t test. D Connection probability was not significantly different in the Chrim⁺→Opsin^- direction compared to the Opsin^-→Chrim⁺ direction.