Fig. 1: Experimental design and summary of annotated lipids across positive and negative ionization modes. | Nature Communications

Fig. 1: Experimental design and summary of annotated lipids across positive and negative ionization modes.

From: Resolving multi-image spatial lipidomic responses to inhaled toxicants by machine learning

Fig. 1: Experimental design and summary of annotated lipids across positive and negative ionization modes.

a Experimental design including allergic sensitization, challenge, and ozone exposure. Left lung lobes were collected 24 h following the final day of ozone exposure. b Summary of all lipid annotations grouped by major class, subclass, and saturation validated by LC-MS/MS of scraped tissue slides and microdissected lung tissue under identical experimental conditions as previously reported12. The individual annotation list is included in Supplementary Data 1 and a supplemental list containing the proportion of lipids in each major class, including saturated and unsaturated lipid species, is included in Supplementary Data 2. Source data for panel b are provided as a Source Data file.

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