Table 1 Summary of key covariates

From: Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube

  

BRCAm

 
 

Non-BRCAm

BRCA1m

BRCA2m

Sum

FTs Collected

70

28

27

125

Use DNA Methylation

59

25

19

103

Use RNAseq

53

22

19

94

Use Proteomics

55

23

18

96

Use All Assays

52

22

18

92

Cell Composition (from DNA methylation)

Stroma Fraction (p = 0.16)

0.58 ± 0.16

0.48 ± 0.13

0.46 ± 0.16

 

Age at Salpingectomy

Age (p = 0.42)

44 ± 13

40 ± 9

42 ± 9

 

Menopause Status

Premenopause

26

19

14

59

Postmenopause

15

3

4

22

Postpartum

Postpartum

11

0

0

11

Self-reported Race

Asian

2

0

0

2

Black

25

2

1

28

White

25

20

16

61

Other

0

0

1

1

Reason For Salpingectomy

Adnexal Mass

1

0

0

1

Cervical Dysplasia

2

0

0

2

Cesarean Section

11

0

0

11

Endometriosis

1

0

0

1

Gender Affirmation

2

0

0

2

Menorrhagia

3

0

0

3

Ovarian Cyst

5

0

0

5

Ovarian Cyst (Sex chord stromal tumor)

1

0

0

1

Ovarian Serous Cystadenoma

2

0

0

2

Pelvic mass

1

0

0

1

Risk Reduction

0

22

18

40

Tubal Sterilization

2

0

0

2

Benign Uterine

21

0

0

21

  1. Table covariate counts and summary statistics are from the 92 samples with all data for RNA expression, DNA methylation, and protein expression. P values are from ANOVA F test. Values represent mean ± standard deviation.
Back to article page