Table 2 Summary of differential testing for DNA methylation, RNA, and protein expression
Contrasted Groups | Model | DMRs (Stouffer’s Pval <0.05) | Differentially Expressed Genes | Differentially Expressed Proteins |
|---|---|---|---|---|
BRCA DIFFERENCES | ||||
BRCAm vs. Non-BRCAm | ~BRCAm | 10 | 3524 | 92 |
BRCAm vs. Non-BRCAm | ~BRCAm + % Stroma | 5 | 1569 | 0 |
BRCAm vs. Non-BRCAm excl. postpartum | ~ BRCAm + % Stroma | 0 | 159 | 0 |
MENOPAUSE DIFFERENCES | ||||
Pre- vs. Post-menopause | ~Menopause Status | 36547 | 5826 | 966 |
Pre- vs. Post-menopause | ~Menopause Status + % Stroma | 164 | 696 | 4 |
Pre- vs. Post-menopause excl. postpartum | ~Menopause Status + % Stroma | 60 | 1769 | 0 |
