Fig. 8: COVA1-27 tracer uptake in the kidneys.

Representative PET signal in the kidneys of CM4 (a), CM8 (b), and CM7 (c), color scale 0–4 SUV. d Longitudinal evaluation of the PET signal SUVmean normalized against that of 0 dpe in the kidneys of animals and e quantification of the mean [89Zr]COVA1-27-DFO PET signal normalized to that of 0 dpe in the kidneys. The exposed + COVA group is indicated in turquoise (circles, squares, hexagons, diamonds, n = 4), the exposed + IgG group in pink (circles, squares, n = 2), and the mock + COVA group in black (triangles, n = 2). Data are presented as individual values the the mean and SD. Source data are provided as a Source data file.