Fig. 4: IDP-membrane interaction profile.
From: Martini3-IDP: improved Martini 3 force field for disordered proteins
A Last frame MD snapshots of Martini3-IDP simulations with CTM (left) binding to a lipid membrane consisting of POPC (70%, dark gray) and POPS (30%, green), TRPV4 (right) binding to a lipid membrane consisting of POPC (70%, dark gray) DOPS (20%, green) as well as PIP2 (10%, light gray). B Probability distribution of the radius of gyration of CTM/TRPV4 under solution condition, comparing Martini 3 and Martini3-IDP. Dotted lines represent the mean value of the distribution and the black solid line denotes the experimental Rg value reported for TRPV459.
