Fig. 2: Proportion of patients reinfected over time in each site and trial arm. | Nature Communications

Fig. 2: Proportion of patients reinfected over time in each site and trial arm.

From: Impact of dhps mutations on sulfadoxine-pyrimethamine protective efficacy and implications for malaria chemoprevention

Fig. 2: Proportion of patients reinfected over time in each site and trial arm.The alternative text for this image may have been generated using AI.

Markers denote the observed proportion infected across trial follow-up among those at risk of new infection, along with error bars representing 95% binomial confidence intervals (Clopper-Pearson method) around the observed proportion (N = 1639 across all trial arms and sites). The denominators for each trial site are shown in Table 1. Colours denote different genotypes. Model predictions from the combined fit are shown by the lines (posterior median) and shaded areas (95% Credible interval), dhps AKA (A437-K540-A581), dhps GKA (437G-K540-A581), dhps GEA (437G-540E-A581), dhps GEG (437G-540E-581G); dhps: dihydropteroate synthase.

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