Fig. 7: Ontology term enrichments.
From: Evolutionary sparse learning reveals the shared genetic basis of convergent traits
Enrichment tests (Fisher’s exact test) were performed for Gene, Phenotype, and Disease ontology terms (see Methods) for the top 100 highest-ranking trait proteins in our echolocation multiple species combination ensemble model integration analysis and in the highest ranking 100 proteins from the other tested methods. P-values are adjusted by the Benjamini-Hochberg method to account for multiple tests (see Supplementary Methods). ASR: Ancestral Sequence Reconstruction; BUSTED: Branch Site Unrestricted Statistical Test of Episodic Diversification41; CCS: Convergence at Conservative Sites7; CSUBST-ωC: Convergent SUBSTitution ωC35; TAAS: Target species specific Amino Acid Substitution42.
