Fig. 6: PVTX-405 shows anti-cancer efficacy in the MC38 mouse tumor xenograft model in immune-competent CrbnI391V C57BL/6 mice. | Nature Communications

Fig. 6: PVTX-405 shows anti-cancer efficacy in the MC38 mouse tumor xenograft model in immune-competent CrbnI391V C57BL/6 mice.

From: Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy

Fig. 6

PVTX-405 or vehicle control was administrated to 10 mice in each group via oral gavage using 100% PEG200 as the dosing vehicle. a Tumor growth for each group. A method of one-tailed t test with Welch’s correction was used for p value calculation. “*”p < 0.05. Data presented as mean ± SEM, with n = 10 animals for each treatment group. b Animal body weight change for each group. Data presented as mean ± SEM, with n = 10 animals for each treatment group. Source data are provided as a Source Data file.

Back to article page