Fig. 1: The Sex Inclusive Research Framework decision tree.
From: The Sex Inclusive Research Framework to address sex bias in preclinical research proposals

Underpinning the Sex Inclusive Research Framework is a decision tree consisting of twelve questions which, when applied to a research proposal, results in the assignment of one or more traffic light outcome classifications. These indicate whether a proposal is appropriate (green thumbs up symbol), carries some risk (amber caution hand symbol) or is insufficient with regards to sex inclusion (red thumbs down symbol).