Fig. 6: The AmVg cleavage product.
a Location of possible cleavage sites of AmVg in its structure and sequence. Possible motifs for cleavage are coloured grey, with basic residues shown in ball-and-stick representation and disulfide bonds coloured yellow. Numbers have been given to the cleavage sites and letters to the b-strands in the cleavage area. The secondary structure of the segments is indicated under the sequence. b Density around the cleavage motifs for the cleavage product at two contour levels representing different confidence levels. Strands a and b are clearly visible at normal contour levels (7σ). What could be residual density for strand c (shown as a dashed orange line) is visible only at low contour levels (1σ). The positions of the different possible cleavage motifs are also shown. Map quality around the cleavage area is quite poor and some regions are modelled as alanine sidechains except for glycine and proline residues. More details regarding the areas modelled as poly-alanine can be found in the Supplementary Information.
