Fig. 3: Sperm H2AK119ub1 is remodelled following exposure to egg factors. | Nature Communications

Fig. 3: Sperm H2AK119ub1 is remodelled following exposure to egg factors.

From: Sperm derived H2AK119ub1 is required for embryonic development in Xenopus laevis

Fig. 3

A Experimental design for monitoring modified histones fate following sperm exposure to egg factors. B Heatmap of H2AK119ub1, H3K4me3, and H3K27me3 signal (log(ChIP/Input)) in spermatid, sperm, replicated sperm, blastula, and gastrula. All genomic locations enriched for one of these histone modifications (peaks) in at least one of these developmental stages are represented. C Venn diagram indicating the changes to H2AK119ub1 (left), H3K4me3 (middle) or overlapping H3K4me3/H2AK119ub1(right) peaks during sperm chromatin replication in egg extract. Percentages of sperm peaks that are maintained after replication are indicated underneath.

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