Table 2 Optimization of the reaction conditions for the synthesis of 29
From: Electrochemical synthesis of allenyl silanes and allenyl boronic esters
| ||
|---|---|---|
Entry | Deviation from standard conditions | % Yielda |
1 | None | 56, 46b |
2 | Na2CO3 or NaOH instead of MeONa | 46, 30 |
3 | Graphite at both the anode and the cathode | NR |
4 | Platinum anode instead of SST | 17 |
5 | LiClO4 instead of Et4NBF4 | 23 |
6 | CH3OH/CH3CN (4:1) instead of CH3OH | 39 |
7 | CH3OH/acetone (4:1) instead of CH3OH | 42 |
8 | rAP = 50 ms instead of 150 ms | 12 |
9 | rAP = 300 ms instead of 150 ms | 39 |
