Table 5 Interventions included in the model

From: An individual-based modelling study estimating the impact of maternity service delivery on health in Malawi

Health system interactionc

Modelled interventions

Antenatal care (Contacts 1–8)

Screening interventions:

• Blood pressure measurement

• Urine dipstick

• Point-of-care haemoglobin testing

• Syphilis testing (rapid plasma reagin)

• HIV testinga

• Gestational diabetes testing (blood glucose)

• Screening for depressiona

• Screening for tuberculosisa

Preventative interventions:

• Daily iron and folic acid supplementation

• Calcium supplementationb

• Balanced energy and protein supplementation

• Antibiotic treatment for syphilis

• Albendazole (deworming)

• Intermittent preventive treatment of malaria during pregnancy (IPTp)

• Insecticide treated bed netsa

• Tetanus toxoid immunisationa

Inpatient antenatal services

Preventative interventions:

• Antibiotics prophylaxis following PROM

• Referral for emergency delivery

Curative interventions:

• Gestational diabetes case management (diet/exercise, oral diabetic medications, insulin)

• Blood transfusion

• Antihypertensive treatment (oral and intravenous)

• Magnesium sulphate

Facility delivery (BEmONC)

Preventative interventions:

• Clean birth practices

• Antibiotics prophylaxis following PROM

• Antenatal corticosteroids following preterm labour

Curative interventions:

• Maternal sepsis case management (intravenous antibiotics)

• Antihypertensive treatment (intravenous)

• Magnesium sulphate

• Assisted vaginal delivery

• Active management of the third stage of labour

• Neonatal stimulation and resuscitation

Facility delivery (CEmONC)

Curative interventions:

• Delivery via caesarean section

• Additional curative surgery (uterine rupture repair/hysterectomy)

• Blood transfusion

Postnatal care (maternal)

Screening interventions:

• HIV testinga

• Screening for depressiona

Preventative interventions:

• Daily iron and folic acid supplementation

Curative interventions:

• Postpartum haemorrhage case management (uterotonics, manual removal of retained placenta, referral for surgery)

• Maternal sepsis case management (intravenous antibiotics)

• Antihypertensive treatment (intravenous)

• Magnesium sulphate

Postnatal care (neonatal)

Screening interventions:

• HIV testinga

Preventative interventions:

• Other essential newborn care – vitamin K prophylaxis, eye care, immunisations

Curative interventions:

• Neonatal sepsis case management – injectable antibiotics

• Neonatal sepsis case management – full supportive care

• Kangaroo mother care

CEmONC – Postnatal

Curative interventions:

• Surgery (management of postpartum haemorrhage)

• Blood transfusion

  1. aThe effect of this intervention on outcomes is determined by the relevant disease model and is therefore not described within the supplementary material of this paper.
  2. bCalcium supplementation is only delivered to women deemed to be at risk of developing pre-eclampsia in line with Malawian guidelines.
  3. cA health system interaction (HSI) is an event in the simulation in which healthcare is delivered. Interventions are housed within HSIs defined by the level of facility at which they occur and the required healthcare worker time.