Fig. 6: Sub-ambient temperature DTCCSD190K He and ATD of α-synuclein [M + 13H]13+. | Nature Communications

Fig. 6: Sub-ambient temperature DTCCSD190K He and ATD of α-synuclein [M + 13H]13+.

From: Conformational landscapes of rigid and flexible molecules explored with variable temperature ion mobility-mass spectrometry

Fig. 6: Sub-ambient temperature DTCCSD190K He and ATD of α-synuclein [M + 13H]13+.

a Fitted DTCCSD190KHe (blue line) and experimental values (black dots) at 5 drift voltages, in decreasing order, at 190 K. b Interconversion rate constant calculation simulation fitted to the ATDs obtained at the lowest drift voltage for which reasonable signal was obtained at: 295, 275, 210, 190 K from top to bottom. Black dots represent experimental values, and solid blue lines of panel (b) represent the calculated fit to the ATD. The schematic of the α-synuclein structure is adapted from AlphaFold Protein Structure Database82.

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