Fig. 8: Analysis of perfusion source map modulations due to neural activation.

a Two-sided T-test results conducted on the perfusion source maps for Subject 1 with bilateral activation (left) and Subject 2 with left motor cortex activation (right). For Subject 1, regions with significant changes in source signal amplitude are identified in veins draining both motor cortices, whereas for Subject 2, significant changes are only identified in the vein draining the left motor cortex. b Four source ROIs are placed at regions showing statistically significant changes. The source signal amplitude of each ROI is displayed across mixing times at baseline and during task. c Blood oxygenation Level Dependent (BOLD) T-scores for the coronal sections containing each vein. Three ROIs are selected on the activated regions determined by the commercial BOLD acquisition. d The percent modulation for each ROI (shown in c) measured by the custom Spiral-BOLD performed between each DiSpect partition is displayed across the entire acquisition. Red markers indicate the last Spiral-BOLD acquisition performed during task, and green markers indicate the last Spiral-BOLD acquisition performed during rest. All three regions exhibit consistent activation throughout the scan. Source data are provided in ref. ⁵⁴.