Fig. 6: Synaptic enrichment of differentially expressed and genetically mediated associations. | Nature Communications

Fig. 6: Synaptic enrichment of differentially expressed and genetically mediated associations.

From: Large-scale transcriptomic analyses of major depressive disorder reveal convergent dysregulation of synaptic pathways in excitatory neurons

Fig. 6: Synaptic enrichment of differentially expressed and genetically mediated associations.

a, b Synaptic Gene Ontology enrichment plots for combined differential expression results in the sACC and Amygdala. c, d Combined QTL features in the sACC and Amygdala, respectively. Enrichment for each SynGO term was tested using a one-sided Fisher’s exact test followed by FDR correction for multiple testing.

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