Fig. 1: Inherently chiral calix[4]arenes and their catalytic enantioselective synthesis.

A Inherently chiral calix[4]arenes and their applications. B Catalytic enantioselective synthesis of ICCs through Pd-catalyzed intramolecular C–H arylation. C Catalytic enantioselective synthesis of ICCs through CPA-catalyzed sequential Povarov reaction and aromatizations. D This work: Catalytic enantioselective synthesis of ICCs through CPA-catalyzed aromatic amination.