Fig. 6: Vibration signals from club neurons are transmitted directly and indirectly to the brain and integrated with mechanosensory signals from the antenna.
From: Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg
A Ascending club axons and ascending 8B and 10B interneurons that are reconstructed in the FANC (bottom, 8 club axons and 52 interneurons) and FlyWire (top, 24 sensory axons and 94 interneuron axons) datasets. B Venn diagrams of shared postsynaptic partners between ascending club neurons and ascending 8B/10B neurons in the VNC (top) and brain (bottom). C Images of the ascending club axons (n = 24) and ascending 8B and 10B interneurons (n = 94) in the brain dataset with targeted brain regions highlighted (FlyWire). Axons project to the anterior ventrolateral protocerebrum (AVLP), wedge (WED), saddle (SAD), and gnathal ganglion (GNG). D Percentage of synaptic outputs from ascending club axons (top) and ascending 8B/10B interneurons (bottom) in each brain region. The ascending club axons and ascending interneurons differ with respect to distribution of output synapse location. E Number of postsynaptic partners of ascending club axons (left) and ascending 8Bs/10Bs (right) that are shared with other sensory neurons in the brain. F Circuit diagram depicting the projection patterns of ascending club and ascending 8B/10B interneurons in the brain, which integrate with antennal mechanosensory circuits. Source data is provided as a Source Data file.
