Fig. 1: Geographic distribution and global ancestry deconvolution of individuals from the BIG initiative.
From: Insights from the Biorepository and Integrative Genomics pediatric resource
a Overview of data collected across four sites in Tennessee, US. b Global ancestry deconvolution of 13,152 sequenced individuals, based on RFMix41 and using reference populations in the 1000 Genomes and Human Genome Diversity Project (HGDP) data sets. Each vertical bar represents one individual, colors are proportional to inferred ancestry. For further analyses, individuals were grouped based on the ancestry proportions in seven categories (colored bar, number of individuals per category in parentheses), and classified as admixed or not (black and gray bar) as described in the text. c Proportion of individuals corresponding to each ancestry stratified by the zip code. Some colors might not be visible, see supplementary Fig. 3 or table for details. d Prevalence of ancestries by zip code - EUR: European; AFR: African; EAS: East-Asian; AMR: Indigenous-American. Maps were produced with the leaflet package (v. 2.2.1) using GeoJSON data for state ZIP-code boundaries publicly available.
