Fig. 1: Cell type-specific expansion in the postnatal pituitary.
From: Gonadotrophs have a dual origin, with most derived from early postnatal pituitary stem cells
A Percentages of endocrine cells from dissociated pituitaries stained for each endocrine hormone (GH for somatotrophs, PRL for lactotrophs, TSH for thyrotrophs, LH for gonadotrophs and POMC for both corticotrophs and melanotrophs) from P5 to one-year-old males and females (n > =3 pituitaries/age/sex, Supplementary Table S1). B Estimated numbers of endocrine cells per pituitary. Total cell numbers were independently counted (Supplementary Fig. 1, Supplementary Table 2) and percentages assessed in A used to estimate the number of cells for each endocrine population. C Evolution of each population: the percentage at each age is shown in relation to the average percentage at P5. The size of dots relates to the proportion of each population in the gland (Supplementary Table S1). D Percentage of EdU-positive cells/marker following a one-hour EdU pulse. Each dot represents one pituitary (n = 3 pituitaries/age/sex, Supplementary Table S3). Source data are provided as a Source Data file.
