Fig. 4: Standardized beta coefficients and their 95% confidence intervals for the associations between obesity-related outcomes and methylation at cg19998400 (X-axis) or mtDNA quantity (Y-axis) (n = 42–142 individuals) in adipose tissue. | Nature Communications

Fig. 4: Standardized beta coefficients and their 95% confidence intervals for the associations between obesity-related outcomes and methylation at cg19998400 (X-axis) or mtDNA quantity (Y-axis) (n = 42–142 individuals) in adipose tissue.

From: Twin pair analysis uncovers links between DNA methylation, mitochondrial DNA quantity and obesity

Fig. 4

Yellow background indicates variables with FDR < 0.05 associated with cg19998400 methylation only, blue indicates variables associated with mtDNA quantity only, and green indicates variables associated with both. Black dots present estimates for standardized beta coefficients, and gray lines represent 95 % confidence intervals. Source data are provided in the Source Data file. ALAT Alanine aminotransferase, ASAT Aspartate aminotransferase, CRP high-sensitivity C-reactive protein, EAA epigenetic age acceleration, BP blood pressure, HDL high-density, LTPA leisure-time physical activity, mtDNAq mitochondrial DNA quantity, Subcut. subcutaneous.

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