Table 1 Participant characteristics
From: Twin pair analysis uncovers links between DNA methylation, mitochondrial DNA quantity and obesity
N (twin pairs, singletons) | 173 (86, 1) |
|---|---|
MZ / DZ (full twin pairs) | 163 (81) / 10 (5) |
Age, mean (range) | 45.7 (22.8–69.3) |
Female, % | 59.0 |
Smoking, % | Never 39.3 Current 30.1 Former 30.6 |
Obesity-related measures, Mean (range) SD | |
Weight (kg) | 83.7 (48.7–143.6) 18.3 |
BMI (kg/m2) | 29.2 (19.7–45.9) 5.8 |
Waist circumference (cm) | 97.6 (65.2–144.3) 15.7 |
WHR | 0.9 (0.8–1.1) 0.1 |
Fat (%) | 36.6 (8.9–57.3) 9.6 |
Fat (kg) | 31.9 (7.4–66.0) 13.0 |
Fat-free mass (kg) | 49.8 (29.5–76.7) 10.8 |
Intra-abdominal fat (cm3) | 1015 (152–3950) 870 |
Subcutaneous fat (cm3) | 4582 (827–15,129) 2830 |
Adipocyte volume (mm3) | 539 (123–1131) 218 |
Liver fat (%) | 2.7 (0.1–22.4) 4.0 |
Total cholesterol (mmol/l) | 4.8 (2.7–7.7) 0.9 |
HDL (mmol/l) | 1.5 (0.5–3) 0.5 |
LDL (mmol/l) | 3 (1–5.1) 0.8 |
Triglycerides (mmol/l) | 1 (0.3–5.9) 0.6 |
hsCRP (mg/l) | 2.3 (0.1–9.7) 2.3 |
Adipsin (µg/ml) | 1.2 (0.7–1.7) 0.2 |
Adiponectin (ng/ml) | 3320 (1310–7710) 1408 |
ALAT (U/l) | 29.3 (14–127) 20.1 |
ASAT (U/l) | 29.2 (7–131) 14.3 |
Systolic blood pressure (mmHg) | 133 (97–195) 19 |
Diastolic blood pressure (mmHg) | 80 (48–110) 78 |
Fasting glucose (mmol/l) | 5.6 (4.0–16.1) 1.1 |
Fasting insulin (mU/l) | 8.1 (0.9–34.3) 5.9 |
HOMA-IR | 2.1 (0.2–9.9) 1.8 |
Matsuda index | 6.7 (0.7–34.2) 4.9 |
Physical activity measures (Baecke scale), Mean (SD) | |
Leisure-time physical activity | 2.9 (0.6) |
Sports activity | 2.7 (0.9) |
Work activity | 2.5 (1.0) |
Total activity | 8.1 (1.5) |
